2017-06-22 15:47:092019-11-15 16:31:36
additional information
term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''yxjB'' [Pubmed|27120414]
a [[protein|NusA]]-dependent terminator and an SD-sequestering hairpin are present in the [[gene|tlrB]] leader [Pubmed|31719185,27120414]
regulatory mechanism
[protein|4910F1E5BAF274C828FD92C410A1B86FB1D358CE|TlrBL]: attenuation, [pubmed|31719185], in [regulon|4910F1E5BAF274C828FD92C410A1B86FB1D358CE|TlrBL regulon]
regulation
induced in the presence of tylosin (transcription attenuation and translation attenuation in the absence of tylosin) [Pubmed|31719185]
induction depends on [[protein|NusG]]-dependent [SW|RNA polymerase] pausing between the leader peptide [[protein|TlrBL]] and [[gene|tlrB]] coding sequences [Pubmed|31719185]